nucid was created from our commitment to improving animal health and performance with innovative solutions. nucid uses the power of organic acids and their glycerides to protect gut health, which plays a major role in the overall animal health, productivity and economic efficiency in animal production.
nucid contains short-chain and medium-chain fatty acids that have strong antimicrobial properties. These acids help control harmful bacteria like Salmonella and E. coli, creating a healthier gut environment.
The glycerides of organic acids in nucid improve intestine morphology by increasing villus height to crypt depth ratio and promoting the expression of tight junction proteins like occludin, claudins, and ZO-1. This strengthens the intestinal epithelium’s barrier function and prevents the translocation of harmful pathogens or toxins.
nucid promotes an anti-inflammatory profile, particularly in the presence of an immune challenge by increasing serum antibodies in circulation and reducing the expression of pro-inflammatory cytokines (TNF-α, IL-6, MyD88 etc).
nucid activates digestive enzymes, helping animals digest nutrients better. This improves feed conversion ratio (FCR) and provides energy to enterocytes, leading to better growth rates and overall performance of livestock.
nucid helps animals absorb minerals better, which is essential for their growth, bone development, and overall health.
At Nuevo, our goal is to deliver the most effective products in order to enhance health and performance of production animals. By ensuring a healthier gut environment, nucid contributes to efficient production and higher productivity.
Our process in developing nucid is rooted in a set of core principles that guide our efforts and reflect our commitment to excellence:
nucid’s performance is based on scientific findings that indicate improved gut health leads to better overall performance. By promoting gut integrity and controlling harmful bacteria and toxins, nucid ensures healthier and more productive livestock.
nucid’s performance as a product enhances health and efficiency. It improves nutrient digestibility and mineral absorption, leading to better growth rates and optimal use of resources.
nucid represents our dedication to continuous improvement and scientific advancement drives us to develop a high-quality solution that is effective and safe.
Various challenges faced in the intensive animal production can negatively affect animal welfare, health and productivity. nucid is designed to promote health and well-being of your livestock and improve economic returns.
nucid is effective against a wide range of bacteria. It works by:
The undissociated form of organic acids in nucid can easily penetrate the cell membranes of harmful bacteria. Once inside, the acid dissociates, releasing hydrogen ions that disrupt the outer membrane, leading to cell death.
nucid aim to create bacteriostasis. Bacteriostasis is the process of stopping bacteria from growing and multiplying without killing them. It keeps the bacteria in check, preventing them from spreading and causing harm. nucid lowers the pH inside the cell and forces bacteria to consume more energy in order to pump cations outside the cell. This prevents the bacteria from growing and multiplying, resulting in bacteriostasis.
nucid helps control and inhibits the development of viruses that can harm your livestock. By maintaining a healthy gut environment, nucid supports the overall immune system of the animals, making them more resilient to viral infections.
A healthy gut is vital for the overall well-being of animals. nucid helps maintain gut integrity by:
The acidification of feed creates an environment that discourages harmful bacteria while promoting the growth of beneficial bacteria.
By enhancing nutrient digestibility and mineral absorption, nucid ensures better growth rates and optimal use of resources.
Natural bioactive components inside nucid enhance the protection of organisms from oxidative and inflammatory damages
nucid’s main ingredients are glycerides of organic acids. The advantages of organic acids glycerides against organic acids’ salts are summarized in the following table:
| Glycerides of organic acids | Ca/Na salts of acids | ||
|---|---|---|---|
| Active component | Glycerides of SCFA & MCFA | Calcium or sodium salts of organic acids | |
| Need of encapsulation | No | Yes, hydrolysis by water | |
| % of dissociation - pH 3 | 0% | 0%, Encapsulation is dissolved until in small intestine (pH about 6) | |
| Efficiency at pH 3/ Antibacterial effect | Yes | No, Encapsulation is dissolved until in small intestine (pH about 6) | |
| Time of dissociation of organic acid after hydrolysis at pH 7 | Never | <1 second immediately after hydrolysis | |
| % of dissociation - pH 7 | 0% | 98-99% | |
| Efficiency in high pH 7 / Antibacterial effect | Yes | No |
Additionally, nucid, due to presence of glycerides, is pH independent, has no smell, neutral taste and is heat stable. nucid is non-corrosive – it does not cause damage by its’ chemical action. It has a stable form, this ensures that nucid remains stable and effective in the feed without losing its beneficial properties.
It is also amphiphilic, which means it can mix well with both water and fats, having both water-loving (hydrophilic) and fat-loving (hydrophobic) parts.
nucid is designed to protect livestock from various harmful factors through different pathways and biochemical processes. Here’s how nucid works to ensure your animals stay healthy and productive:
nucid acts as an antimicrobial agent, directly killing harmful microorganisms. This immediate reduction in pathogens decreases the chances of infections.
nucid inhibits the growth and reproduction of pathogens.
nucid helps prevent the growth of antimicrobial-resistant microbes. This ensures that effective treatments remain available for infectious diseases, providing continued protection against microbial hazards.
By reducing the number of harmful microbes, nucid lessens the burden on the immune system, allowing animals to stay healthier.
nucid acts as an energy source for enterocytes, helping to improve the energy balance in animals.
nucid protects livestock from stress-related damages through different pathways and biochemical processes that occur during the production period. By regulating cellular functions, nucid ensures that animals fed with diets including nucid have:
Choose nucid for a comprehensive solution to enhance the health, performance, and productivity of your livestock.
A synopsis of nucid supplementation on poultry performance and quality parameters is listed below:
Broilers
| TRAIT | IMPROVEMENT (%) |
|---|---|
| Body weight | 2-3,7 |
| FCR | 3,9-6,3 |
| EPEF | 5,9-12,4 |
| Mortality | 18,5-31,9 |
Laying hens
| TRAIT | IMPROVEMENT (%) |
|---|---|
| Laying rate | 4,9 |
| Egg weight | 0,65 |
Broilers
| TRAIT | IMPROVEMENT (%) |
|---|---|
| Carcass yield | 3,5-5,8 |
| Breast fillet yield | 5,1-10 |
Laying hens
| TRAIT | IMPROVEMENT (%) |
|---|---|
| Haugh unit | 4,9 |
| Egg weight | 6,8 |
Analytical results of the conducted trials are listed at this link.
nucid consists of organic acids in glycerides’ form (mono-, di- and tri- glycerides)
The main benefits of glycerides in comparison with organic acid salts are summarized in the following table
| Glycerides of organic acids | Ca/Na salts of acids | |
|---|---|---|
| Active component | Glycerides of SCFA & MCFA | Calcium or sodium salts of organic acids |
| Need of encapsulation | No | Yes, hydrolysis by water |
| % of dissociation - pH 3 | 0% | 0% ,Encapsulation is dissolved until in small intestine (pH about 6) |
| Efficiency at pH 3/ Antibacterial effect | Yes | No, Encapsulation is dissolved until in small intestine (pH about 6) |
| Time of dissociation of organic acid after hydrolysis at pH 7 | Never | <1 second immediately after hydrolysis |
| % of dissociation - pH 7 | 0% | 98-99% |
| Efficiency in high pH 7 / Antibacterial effect | Yes | No |
Yes, because nucid has no smell, has a neutral taste and is non-corrosive and non-volatile
In addition to glycerides of organic acids, nucid contains a blend of natural bioactive substances with cytoprotective and anti-inflammatory properties
No, nucid ingredients function as adjuvants for animals’ intestinal microbiome by the protection of organism against pathogens and minimization of dysbiosis